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How Exactly Does Jardiance Work?

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Key Aspects
Jardiance is a sodium-glucose -cotransporter-2 (SGLT-2) inhibitor, which is utilized in addition to exercise and diet to control the blood sugar (sugar) for adults suffering from diabetics of type 2. It reduces blood sugar levels by blocking proteins in the kidney to boost the excretion of glucose through urine.

Jardiance can reduce the risk of a heart-related death (like a heart attack or stroke) in adults who have heart disease. It reduces the risk of hospitalization and death due to heart failure (when you have a weak heart and can’t deliver enough blood to other organs part of your body) for patients suffering from heart failure.

As time passes, high blood sugar levels may cause plaque to build up in your blood vessels, increasing your risk of suffering from heart disease.

How does Jardiance function?

Jardiance (empagliflozin) is classified as an SGLT-2 (sodium-glucose cotransporter-2) inhibitor. The SGLT-2 proteins reside in renal tubules of the kidneys. They play a role in taking glucose and reintroducing it back into blood. Jardiance inhibits the function of the SGLT-2 proteins. This means that more glucose is excreted from the urine.

SGLT-2 inhibitors have been proven to be effective in lower levels of hemoglobin A1C which can aid in weight loss as well as lowering blood pressure.

Jardiance can be incorporated into other medicines used to treat type 2 diabetes, such as pioglitazone and metformin as well as sulfony and insulin as well alongside other heart medications, such as beta blockers, statins, ACE inhibitors and diuretics.

If used on their own, SGLT-2 inhibitors have a lower risk of the condition known as hypoglycemia (low glucose levels). However, your doctor may require lowering the dose of Jardiance in the event that you use it in conjunction with other medications that can cause low blood sugarlevels, such insulin or sulfonylureas.

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Other FDA approved medications in the SGLT-2 inhibitor class include:

canagliflozin (Invokana)
dapagliflozin (Farxiga)
ertugliflozin (Steglatro)

These medicines come as single-ingredient products , or when combined with other diabetes medications.

What is the best way to help Jardiance help me with my diabetes type 2?

If you have type 2 diabetes, your body does not make enough insulin. The insulin that you make doesn’t work as effectively and you could produce excess sugar (sugar). As this happens, glucose is accumulating in your bloodstream and could result in serious health problems that affect the kidney, heart blood vessels, nerves and eyes. Exercise, diet, and the use of specific medications will help lower your blood sugar and risks from type 2 diabetes.

A lot of patients who are discovered to have type 2 diabetes are with an oral medication referred to as metformin. It’s part of the class of drugs known as biguanides. It increases the cells ability to make use of glucose (blood sugar) by improving how insulin functions and reduces the absorption of glucose from your liver.

However, some patients can’t achieve their blood sugar goals without metformin and may require additional medication.

Jardiance can be incorporated into metformin or other medicines to help you reach your A1C target. A1C is a simple blood test that displays the average level of sugar (glucose) in your blood in the last 2 to 3 months, which will let you know how your blood sugar levels are being managed over the course of time.

Who is not a good candidate for Jardiance?

Jardiance should never be used in patients suffering from the type one diabetes condition or diabetes-related ketoacidosis (increased ketones in urine or in the blood). Patients suffering from type 1 diabetes could increase the risk of diabetic ketoacidosis among these patients.
It is not recommended to use Jardiance in the event that you’ve experienced an extremely allergic reaction to Jardiance or any of its ingredients.
Also, you should not take this drug if you have an extremely severe kidney (renal) disease or end-stage renal disease or are on dialysis. Your doctor will check your kidney function prior to you begin therapy with Jardiance. Jardiance could not work in the case of severe kidney issues.

How do I take Jardiance?

Take Jardiance daily, exactly the way your doctor advises. It is available in a 20 mg and 25 mg tablets that you swallow.

The recommended dose of Jardiance can be 10 mg every morning in the morning either with or without food. If you’re not tolerant to Jardiance, the dose may be increased by 25 mg should you require it.

Your doctor will check your kidney function using an in-person blood test prior to you begin treatment. If you have a certain amount of kidney disease you may not be able to use Jardiance.

Do not consume Jardiance in case you are allergic to any of its ingredients.

Jardiance is not suitable to be used by anyone younger than 18 years old.

Important side effects with Jardiance

Jardiance is generally well-tolerated. However, as with any drug, there are some serious side effects. You need to discuss these with your physician.

The most serious side effects associated with Jardiance may be:

Ketoacidosis (increased ketones in your blood or urine)
Sudden kidney injury
Urinary tract infections
It is a condition that causes dehydration (the loss of body water and salt)
Blood sugar levels are low (hypoglycemia)
Necrotizing fasciitis (a extremely rare, but severe tissue inflammation of the skin that can develop around the anus and genitals)
Allergic reactions
Increased cholesterol

The most frequently reported adverse symptoms (5 5 percent or more) that could occur with Jardiance are:

Urinary tract infections
Yeast infections